Glucagon anticorps (N-Term)
Aperçu rapide pour Glucagon anticorps (N-Term) (ABIN318563)
Antigène
Voir toutes Glucagon (GCG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-12, N-Term
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Specificité
- This antibody recognises the pancreatic polypeptide hormone Glucagon, whose actions are antagonistic to insulin. Tumours arising from glucagon producing cells are termed glucagonomas, and this antibody may be useful in identifying such tumours.
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Purification
- Purified IgG prepared by affinity chromatography on Protein G
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Immunogène
- Porcine glucagon, amino acids 1-12, conjugated with bTG.
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Isotype
- IgG
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Indications d'application
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 5.0 mg/mL
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Buffer
- PBS, 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Glucagon (GCG)
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Autre désignation
- Glucagon
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Sujet
- Glucagon is a hormone that is secreted by alpha cells in the pancreas. Glucagon antagonizes insulin by converting glycogen to glucose in the liver and increasing blood sugar levels. Glucagon-like peptide 1 (GLP1), Glucagon-like peptide 2 (GLP2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are in the glucagons hormone family. GLP1 is a transmitter in the central nervous system that regulates feeding and drinking behavior. GLP2 stimulates intestinal epithelial growth.Synonyms: GCG
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ID gène
- 2641
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NCBI Accession
- NP_002045
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UniProt
- P01275
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
Antigène
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